Case studies in hematology and coagulation Download case studies in hematology and coagulation or read online books in PDF, EPUB, Tuebl, and Mobi Format. Click Download or Read Online button to get case studies in hematology and coagulation book now. This site is like a library, Use search box in the widget to get ebook that you want. Hematology 2012 2012:191; 10.1182/asheducation-2012.1.191 DIFFERENTIATE PHYSIOLOGICAL MECHANISMS Low PLT + Normal/Low IPF (Consistent with production disorder) Normal Low PLT+ High IPF (Consistent with destruction disorders). Hematology Case Studies -CLSA 2017 ().
CASE 2: A 26-year-old American female was treated for excessive joint pains, swollen ankles and fever over a period of years with analgesics and other pain therapy. Her physical examination revealed signs of inflammation, splenomegaly, and some bacterial infection. Initial Laboratory Profile: WBC 15.5x 10 9/L (4.8-10.8)N MCV 91fl (80-96)N RBC 3.5 X1012/L (4.2- 5.5) N MCH 29. 8 pg ( 27-32)N Hb 10.
5gm/dl ( 12-16) N MCHC 32. 4% ( 32-36)N Hct 31.6% (37-47) N Sed Rate 30/ mm/hr (0-20)N 1. What category of anemia is suggested here? CASE 3: A 24-year-old female on her first visit to her physician complained of weakness and being continually tired. She also stated that she had lost an appreciable amount of weight. There was no family history of anemia, but evidence was produced that she had abused the use of alcohol by consuming several quarts weekly, and neglected having a normal diet for several years.
Initial Laboratory Profile RBC 3.0 X 10 12/L ( 4.2-4.5) N MCV 92 fl (78-96) N WBC 9.7 X 10 9/ L ( 4.8-10.8) N MCH 30.9 (27-32) N Hct 26.9% ( 37-47) N MCHC 33.5 ( 32-36) N Hb 9.0 gm/dL ( 12-14) N RDW 15.0 (11.5-14.5) N 1. What is the category of this anemia? CASE 4: 23 year old male. Over the past week noted increasing fatigue, sore throat, earaches, headaches, and episodic fever and chills. Unable to run his customary 25 miles per week.
Physical Exam: Erythematous throat and tonsils. Swollen cervical lymph nodes. CBC (with microscopic differential) RBC 5.25 x 1012/L HGB 15.4 g/dL HCT 46.1% MCV 87.9 fL MCH 29.3 pg MCHC 33.4 g/dL RDW 12.2 WBC 12.9 x 109/L N 24% L (shown) 73 M 0 E 3 B 0 PLT 333 x 109/L Morphologic Alterations Results of the blood smear exam were: RBC morphology: Normocytic, normochromic WBC morphology: Most of the lymphocytes are reactive.
They are large cells with a smudged chromatin pattern and abundant cytoplasm with radial and/or peripheral basophilia. Some of the larger cells have finer chromatin and nucleoli. PLT morphology: Within normal limits 1. What further laboratory studies, if any, are indicated? CASE 5: 70 year old female.
Symptoms of dyspnea on exertion, easy fatigability, and lassitude for past 2 to 3 months. Denied hemoptysis, GI, or vaginal bleeding. Claimed diet was good, but appetite varied.
Physical Exam: Other than pallor, no significant physical findings were noted. Occult blood was negative. CBC (with microscopic differential) RBC 3.71 x 1012/L HGB 5.9 g/dL HCT 20.9% MCV 56.2 fL MCH 15.9 pg MCHC 28.3 g/dL RDW 20.2 WBC 5.9 x 109/L N 82% L 13 M 1 E 4 B 0 PLT 383 x 109/L Results of the blood smear exam were: RBC morphology: 2+ hypochromasia 3+ microcytosis 2+ anisocytosis 2+ elliptocytes and target cells occ teardrops and fragments WBC morphology: Within normal limits (one lymphocyte shown here) PLT morphology: Within normal limits 1. What further laboratory studies, if any, are indicated? CASE 6: 51 year old male. Seen by local physician for routine preoperative exam prior to dental surgery. Found to have low hemoglobin and a large left upper quadrant mass. Device software update utility htc m9 plus.
Physical Exam Marked splenomegaly (subsequently confirmed by CT scan) extending from the left costal margin to just above the iliac crest. No other organomegaly. CBC (with microscopic differential) RBC 3.36 x 1012/L HGB 10.9 g/dL HCT 31.2% MCV 92.8 fL MCH 32.4 pg MCHC 34.9 g/dL WBC 9.3 x 109/L N 14% L 15 abnormal cells 71 (shown) PLT 59 x 109/L Morphologic Alterations Results of the blood smear exam were: RBC morphology: Normocytic, normochromic WBC morphology: The abnormal cells have round or indented nuclei with a fairly coarse chromatin pattern. They have variable amounts of grainy blue-gray cytoplasm with irregular ragged borders and numerous projections. PLT morphology: Within normal limits 1. What further laboratory studies, if any, are indicated? CASE 7: 25 year old male.
Recurrent upper respiratory infections with fever, nausea, and submandibular swelling for several months prior to admission. Noted that cuts on his hands did not heal well. Physical Exam Submandibular adenopathy. No other organomegaly. CBC (with microscopic differential) RBC 2.70 x 1012/L HGB 9.9 g/dL HCT 28.7% MCV 106.3 fL MCH 36.9 pg MCHC 34.8 g/dL WBC 7.9 x 109/L N 4% L 16 M 1 E 0 B 0 abnormal cells 79 (shown) PLT 50 x 109/L Morphologic Alterations Results of the blood smear exam were: RBC morphology: Normochromic 1+ polychromasia 1+ macrocytosis WBC morphology: The abnormal cells are medium-sized blasts. The nuclei are often irregular in shape, and some have invaginations or deep clefts. Most have a fine chromatin pattern and one or more prominent nucleoli.